%title Therapeutic indecies (note to self, but it's interesting)
%date 2005-06-19 08:21:29
:diary:livejournal:fossils:

<details text="Drugs! *snp*"><summary>Drugs! *snp*</summary>(Ratio of LD50 [the lethal dose for 50% of the population] to the 'standard dose')

Tobacco - 2***
Heroin (street, IV) - ~4.5* (see below)
Alcohol - 5
Diacetylmorphine HCl (IV) - 8*
Methylamphetamine (IV) - ~8*
GHB - 10**
Coffee (caffeine) - 125
Absinthe (thujone) - 1,200
Marijuana (Δ<sup>9</sup>-THC) - 40,000
Salvia (salvinorin A) - Uh...

* Best I can figure.
** This is based of the 'poisoning' dosage - there is risk of death at lower dosages, but the most common effect is a 5-hour coma, death resulting from choking on vomit or other such things (as with alcohol).
***I'm not really sure where this came from, actually o.o  There's a chance that it's right for nicotine, but I'm not sure.  The problem with TIs for tobacco is the method of ingestion (1 cigarette is a normal dose, and the only dose there is, really) as well as the excedingly long (1,000+) ingredient list for a standard cigarette.  Not to mention that's not the only method of ingestion.

Sources: Erowid.org, Dale Pendell - <em>Pharmako/poeia</em> and <em>Pharmako/dynamis</em>

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